Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27338316 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL8617883 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP3A4HPRT1KDM4E | |
| SCHEMBL8623600 | 0.78 | NCEH1 (0.37) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL6171290 | 0.78 | MAPT (0.38) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL8620493 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL680370 | 0.74 | AKR1B1 (0.40) | ALDH1A1HSD17B10TSHRKDM4EMEN1 | |
| SCHEMBL7353058 | 0.73 | CA12 (0.44) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL21555507 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL23961077 | 0.68 | CA1 (0.36) | ALDH1A1HSD17B10HPGDHPRT1KDM4E | |
| Acetonitrile SCHEMBL27651258 | 0.67 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1041935-C | Benzo[f]quinoxalindione derivatives, their preparation and their use in drugs | SCHERING AG (DE) | 1999-02-03 | — | — | CN | disclosed |
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| CN-1122136-A | Benzo[f]quinoxalindione derivatives, their preparation and their use in drugs | SCHERING AG (DE) | 1996-05-08 | — | — | CN | disclosed |
| EP-0696289-A1 | BENZO F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |