Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 7/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.31 |
| ▸ | AR | P10275 | 5/20 | 0.31 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618594 | 0.85 | PGR (0.38) | PGRNR3C1AR | |
| SCHEMBL8409402 | 0.81 | CYP1B1 (0.42) | CYP17A1PGRARCYP21A2 | |
| SCHEMBL8409400 | 0.78 | PGR (0.44) | CYP17A1PGRNR3C1AR | |
| SCHEMBL8410183 | 0.72 | PGR (0.32) | PGR | |
| SCHEMBL8407453 | 0.71 | PGR (0.34) | PGRNR3C1AR | |
| SCHEMBL8409732 | 0.70 | PGR (0.35) | CYP17A1PGRCYP21A2 | |
| SCHEMBL9171269 | 0.67 | CYP17A1 (0.33) | CYP17A1PGRARCYP21A2 | |
| SCHEMBL8767774 | 0.66 | — | — | |
| SCHEMBL9019827 | 0.66 | NR3C1 (0.59) | PGRNR3C1AR | |
| SCHEMBL8407415 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |