SCHEMBL861866

SCHEMBL861866

CC1(C)OB(c2ccccc2C=O)OC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LPL P06858 6/20 0.42
LIPG Q9Y5X9 6/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
P4HB P07237 1/20 0.37
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1468223 0.84 JAK2 (0.40) LMNAMEN1THRBBLMKMT2A
SCHEMBL21920287 0.83 JAK2 (0.37) LMNAMEN1THRBBLMKMT2A
SCHEMBL12074929 0.83 JAK2 (0.37) LMNAMEN1THRBBLMKMT2A
SCHEMBL325722 0.81 LPL (0.42) LPLLIPGALDH1A1P4HB
SCHEMBL24621434 0.80 LPL (0.33) LMNAMEN1THRBBLMKMT2A
SCHEMBL1293106 0.80 LIPG (0.35) LMNAMEN1THRBBLMKMT2A
SCHEMBL3040438 0.80 LPL (0.38) LMNAMEN1THRBBLMKMT2A
SCHEMBL29793277 0.80 LPL (0.38) LMNAMEN1THRBBLMKMT2A
SCHEMBL5899734 0.80 LPL (0.54) LPLLIPGP4HBCA1CA2
SCHEMBL15077376 0.79 MEN1 (0.39) LMNAMEN1THRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285960-A Fluorescent probe and preparation method and application thereof 济南大学 2025-01-10 CN claimed
CN-119080812-A Keli boron preparation method of herba Luo 济宁晟泰药业有限公司 2024-12-06 CN claimed
CN-109060739-B Method for detecting hydrogen peroxide 中国科学院上海微系统与信息技术研究所 2021-02-05 CN claimed
EP-4680612-A1 CHEMICAL COMPOUNDS AN2 Therapeutics, Inc. (US) 2026-01-21 EP disclosed
WO-2025235840-A1 ECHINOCANDIN-LIKE AND BORON-CONTAINING ECHINOCANDIN COMPOUNDS AND THEIR USE AS AGROCHEMICAL FUNGICIDES 5METIS, INC. (US) 2025-11-13 WO disclosed
CN-119285960-A Fluorescent probe and preparation method and application thereof 济南大学 2025-01-10 CN disclosed
CN-119080812-A Keli boron preparation method of herba Luo 济宁晟泰药业有限公司 2024-12-06 CN disclosed
WO-2024192309-A1 CHEMICAL COMPOUNDS REACTIVE BIOSCIENCES, INC. (US) 2024-09-19 WO disclosed
CN-115141188-B Substituted quinazoline compound, pharmaceutical composition and application thereof 江南大学 2024-08-23 CN disclosed
CN-116376125-A Hyaluronic acid-based hydrogel and preparation method thereof 中国科学院长春应用化学研究所 2023-07-04 CN disclosed
CN-116217917-A Polyethylene glycol derivative, preparation method thereof, polyethylene glycol hydrogel and preparation method thereof 中国科学院长春应用化学研究所 2023-06-06 CN disclosed
US-7816344-B2 oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics ANACOR PHARMACEUTICALS, INC. (US) 2010-10-19 US disclosed
US-20100256092-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2010-10-07 US disclosed
WO-2009140309-A2 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2009-11-19 WO disclosed
US-20090227541-A1 oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics ANACOR PHARMACEUTICALS, INC. (US) 2009-09-10 US disclosed
US-20090215908-A1 TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST RELIANCE LIFE SCIENCES PVT. LTD. (IN) 2009-08-27 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
EP-1836174-A2 ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS AMGEN INC. (US) 2007-09-26 EP disclosed
WO-2006039718-A2 ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS AMGEN INC (US) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215908-A1 TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST TLR4, TLR5, TLR1 LMNA 4815/4885MEN1 4712/4885THRB 966/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C LMNA 3180/4885MEN1 1124/4885THRB 4550/4885
US-20090227541-A1 oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics OXA1L, TLR1, OXER1 LMNA 3968/4885MEN1 3905/4885THRB 3572/4885
US-20100256092-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BCL6, BTD LMNA 3490/4885MEN1 818/4885THRB 694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.