Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617290 | 0.78 | ICMT (0.31) | TACR1 | |
| SCHEMBL14778250 | 0.74 | TSHR (0.46) | L3MBTL1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4463625 | 0.72 | CYP19A1 (0.41) | TSHRMAPK1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL14778741 | 0.68 | TSHR (0.41) | L3MBTL1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL14779003 | 0.68 | TSHR (0.41) | L3MBTL1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL12197925 | 0.65 | L3MBTL1 (0.44) | L3MBTL1TSHRMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL4611158 | 0.65 | OPRM1 (0.33) | SMN1; SMN2ALDH1A1TACR1 | |
| SCHEMBL9227296 | 0.65 | — | — | |
| SCHEMBL2286730 | 0.65 | KDM1A (0.42) | L3MBTL1TSHRMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL11981415 | 0.64 | ACACB (0.37) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |