SCHEMBL8619409

SCHEMBL8619409

C/C=C/C(=O)O[C@H]1CC[C@H](C(=O)O[C@H]2CC[C@H](CCCCC)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.40
HTT P42858 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
NAAA Q02083 3/20 0.39
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
CCR2 P41597 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
MAPT P10636 3/20 0.34
GAA P10253 1/20 0.34
GNAI3 P08754 1/20 0.30
GNAO1 P09471 1/20 0.30
GNAI1 P63096 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8619547 0.99 HTT (0.41) PKMHTTMEN1KMT2ACYP1A2
SCHEMBL8617899 0.99 HTT (0.41) PKMHTTMEN1KMT2ACYP1A2
SCHEMBL8621538 0.96 PKM (0.38) PKMHTTMEN1KMT2ACYP1A2
SCHEMBL8624148 0.96 NAAA (0.42) PKMHTTMEN1KMT2ACYP1A2
SCHEMBL8622958 0.95 HTT (0.39) PKMHTTMEN1KMT2ACYP1A2
SCHEMBL8622442 0.95 HTT (0.39) PKMHTTMEN1KMT2ACYP1A2
SCHEMBL8617373 0.93 NAAA (0.40) PKMHTTMEN1KMT2ACYP1A2
SCHEMBL8624341 0.91 NAAA (0.33) CYP2C9NAAAPOLBHPGD
SCHEMBL9560329 0.88 PKM (0.49) PKMHTTMEN1KMT2ACYP1A2
SCHEMBL10481696 0.88 PKM (0.49) PKMHTTMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595144-B1 Cyclohexyl alkenoates as components of liquid crystalline mixtures MERCK PATENT GMBH (DE) 1998-05-20 EP disclosed
US-5380462-A Cyclohexyl alkenoate compounds HOFFMANN-LA ROCHE INC. (US) 1995-01-10 US disclosed
EP-0595144-A1 Cyclohexyl alkenoates as components of liquid crystalline mixtures F. HOFFMANN-LA ROCHE AG (CH) 1994-05-04 EP disclosed