SCHEMBL8624341

SCHEMBL8624341

C/C=C/C(=O)O[C@H]1CC[C@H](C(=O)O[C@H]2CC[C@H](CCC)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.33
CYP2C9 P11712 1/20 0.31
POLB P06746 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8622084 0.96 TLR4 (0.33) NAAA
SCHEMBL8624148 0.92 NAAA (0.42) NAAACYP2C9POLBHPGD
SCHEMBL8619409 0.91 PKM (0.40) NAAACYP2C9POLBHPGD
SCHEMBL8643469 0.90 NAAA (0.36) NAAACYP2C9
SCHEMBL8617899 0.90 HTT (0.41) NAAACYP2C9POLBHPGD
SCHEMBL8619547 0.90 HTT (0.41) NAAACYP2C9POLBHPGD
SCHEMBL9185396 0.89 CYP19A1 (0.38)
SCHEMBL8617373 0.89 NAAA (0.40) NAAACYP2C9POLBHPGD
SCHEMBL8621538 0.87 PKM (0.38) NAAACYP2C9POLBHPGD
SCHEMBL11218030 0.87 NAAA (0.40) NAAACYP2C9POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595144-B1 Cyclohexyl alkenoates as components of liquid crystalline mixtures MERCK PATENT GMBH (DE) 1998-05-20 EP disclosed
US-5380462-A Cyclohexyl alkenoate compounds HOFFMANN-LA ROCHE INC. (US) 1995-01-10 US disclosed
EP-0595144-A1 Cyclohexyl alkenoates as components of liquid crystalline mixtures F. HOFFMANN-LA ROCHE AG (CH) 1994-05-04 EP disclosed