Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617373 | 0.96 | NAAA (0.40) | NAAAPOLBHPGDHTTLMNA | |
| SCHEMBL8619409 | 0.96 | PKM (0.40) | NAAAPOLBHPGDHTTLMNA | |
| SCHEMBL8619547 | 0.95 | HTT (0.41) | NAAAPOLBHPGDHTTLMNA | |
| SCHEMBL8617899 | 0.95 | HTT (0.41) | NAAAPOLBHPGDHTTLMNA | |
| SCHEMBL8621538 | 0.93 | PKM (0.38) | NAAAPOLBHPGDHTTLMNA | |
| SCHEMBL8624341 | 0.92 | NAAA (0.33) | NAAAPOLBHPGDCYP2C9 | |
| SCHEMBL8622442 | 0.92 | HTT (0.39) | NAAAPOLBHPGDHTTLMNA | |
| SCHEMBL8622958 | 0.92 | HTT (0.39) | NAAAPOLBHPGDHTTLMNA | |
| SCHEMBL8622084 | 0.88 | TLR4 (0.33) | NAAA | |
| SCHEMBL9876191 | 0.87 | NAAA (0.50) | NAAAPOLBHPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595144-B1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | MERCK PATENT GMBH (DE) | 1998-05-20 | — | — | EP | disclosed |
| US-5380462-A | Cyclohexyl alkenoate compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |