SCHEMBL8619713

SCHEMBL8619713

CC(C)=CCC/C(C)=C/CC(/C=C(\C)CCC=C(C)C)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ICMT O60725 4/20 0.50
MAPT P10636 2/20 0.50
GMNN O75496 1/20 0.50
TRPA1 O75762 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50
CDK2 P24941 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
HSD17B10 Q99714 1/20 0.50
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
TRPV1 Q8NER1 2/20 0.43
GGPS1 O95749 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6445161 0.87 TRPV1 (0.47) ICMTMAPTGMNNTRPA1LMNA
SCHEMBL8625201 0.85 ICMT (0.40) ICMTMAPTGMNNTRPA1LMNA
SCHEMBL8625837 0.85 ICMT (0.40) ICMTMAPTGMNNTRPA1LMNA
SCHEMBL8623311 0.84 LMNA (0.53) ICMTMAPTGMNNTRPA1LMNA
SCHEMBL8625198 0.83 TRPV1 (0.46) ICMTMAPTGMNNTRPA1LMNA
SCHEMBL8620652 0.80 TRPV1 (0.36) ICMTMAPTGMNNTRPA1LMNA
SCHEMBL8618525 0.80 TRPV1 (0.50) MAPTLMNAFNTAFNTBTRPV1
SCHEMBL8646997 0.80 TRPV1 (0.46) ICMTFNTAFNTBTRPV1
SCHEMBL8624938 0.79 TRPV1 (0.43) ICMTMAPTGMNNTRPA1LMNA
SCHEMBL8620646 0.79 TRPV1 (0.42) ICMTMAPTFNTAFNTBTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711749-B1 Process for producing geranylgeraniol KURARAY CO (JP) 1998-05-20 EP disclosed
US-5663461-A HYDROLYSIS OF ESTER KURARAY CO., LTD. (JP) 1997-09-02 US disclosed
EP-0711749-A1 Process for producing geranylgeraniol KURARAY CO., LTD. (JP) 1996-05-15 EP disclosed