Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619890 | 0.80 | LGALS3 (0.47) | POLBLGALS3 | |
| SCHEMBL8620005 | 0.72 | DOT1L (0.44) | LMNAALDH1A1MTORGMNNNFKB1 | |
| SCHEMBL4410427 | 0.69 | DHFR (0.33) | — | |
| SCHEMBL3209557 | 0.67 | HTR6 (0.36) | PNP | |
| SCHEMBL23880690 | 0.67 | CYP2D6 (0.33) | CYP2C19 | |
| SCHEMBL29974422 | 0.67 | CYP2D6 (0.33) | CYP2C19 | |
| SCHEMBL3188454 | 0.66 | HTR6 (0.38) | PNP | |
| SCHEMBL17262432 | 0.66 | PYGL (0.46) | LMNAALDH1A1MTORGMNNNFKB1 | |
| SCHEMBL539348 | 0.66 | PYGL (0.46) | LMNAALDH1A1MTORGMNNNFKB1 | |
| SCHEMBL28707545 | 0.66 | PYGL (0.46) | LMNAALDH1A1MTORGMNNNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686150-B1 | Process for the preparation of C-nucleosides and C-nucleoside analogues, new C-nucleosides and C-nucleoside analogues and their use | MAX DELBRUECK CENTRUM (DE) | 1998-05-20 | — | — | EP | disclosed |