SCHEMBL8619918

SCHEMBL8619918

CCNc1ccc(S(=O)(=O)O)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
RECQL P46063 1/20 0.43
LMNA P02545 3/20 0.42
SNCA P37840 1/20 0.41
ALDH1A1 P00352 7/20 0.38
GAA P10253 3/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 2/20 0.38
GFER P55789 2/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
PLEC Q15149 1/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA12 O43570 2/20 0.38
CA7 P43166 2/20 0.38
CA14 Q9ULX7 2/20 0.38
HCAR3 P49019 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6660835 0.86 CYP3A4 (0.56) CYP3A4TSHRRECQLLMNASNCA
SCHEMBL9329057 0.83 TIMP3 (0.48) RECQLLMNASNCAALDH1A1GAA
SCHEMBL30197886 0.80 ALDH1A1 (0.34) CYP3A4TSHRRECQLLMNASNCA
SCHEMBL13046350 0.80 ALDH1A1 (0.34) CYP3A4TSHRRECQLLMNASNCA
SCHEMBL14364002 0.80 SNCA (0.44) TSHRLMNASNCAALDH1A1GAA
SCHEMBL9327344 0.79 LMNA (0.44) CYP3A4TSHRRECQLLMNASNCA
Sulfuric Acid SCHEMBL9300936 0.79 RECQL (0.43) CYP3A4TSHRRECQLLMNAALDH1A1
SCHEMBL3319072 0.79 KDM4E (0.53) LMNAALDH1A1GAAMAPTKDM4E
SCHEMBL11715144 0.79 CA1 (0.43) TSHRLMNASNCAALDH1A1GAA
SCHEMBL5750382 0.78 MAPT (0.41) LMNAMAPTCA2HCAR3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1046751-C Monozao reactive dyes ZENECA LTD (GB) 1999-11-24 CN disclosed
EP-0692003-B1 MONOAZO REACTIVE DYES ZENECA LTD (GB) 1998-05-27 EP disclosed
US-5614613-A Monoazo reactive dyes ZENECA LIMITED (GB) 1997-03-25 US disclosed
CN-1120344-A Monoazo Reactive Dyes ZENECA LTD (GB) 1996-04-10 CN disclosed
EP-0692003-A1 MONOAZO REACTIVE DYES ZENECA LIMITED (GB) 1996-01-17 EP disclosed
WO-1994022961-A1 MONOAZO REACTIVE DYES ZENECA LIMITED (GB) 1994-10-13 WO disclosed