Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620053 | 1.00 | HSD11B1 (0.40) | HSD11B1GAAL3MBTL1ALDH1A1KCNH2 | |
| SCHEMBL8870143 | 1.00 | HSD11B1 (0.40) | HSD11B1GAAL3MBTL1ALDH1A1KCNH2 | |
| SCHEMBL19433531 | 0.86 | SMN1; SMN2 (0.45) | HSD11B1L3MBTL1ALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL9368035 | 0.85 | L3MBTL1 (0.40) | HSD11B1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9372634 | 0.84 | HSD11B1 (0.38) | HSD11B1L3MBTL1ALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL9368025 | 0.84 | HSD11B1 (0.38) | HSD11B1L3MBTL1ALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL4170321 | 0.82 | MMP1 (0.39) | HSD11B1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9368218 | 0.82 | HSD11B1 (0.38) | HSD11B1L3MBTL1ALDH1A1KCNH2TSHR | |
| SCHEMBL18716489 | 0.81 | HSD11B1 (0.39) | HSD11B1L3MBTL1ALDH1A1KCNH2TSHR | |
| SCHEMBL18716488 | 0.81 | HSD11B1 (0.39) | HSD11B1L3MBTL1ALDH1A1KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716948-A | 3-substituted carbacephems | PFIZER INC. (US) | 1998-02-10 | — | — | US | disclosed |