Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492022 | 0.73 | LTA4H (0.34) | RAB9ARELA | |
| SCHEMBL7207522 | 0.68 | MEN1 (0.31) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8489503 | 0.68 | CDC7 (0.30) | — | |
| SCHEMBL8617142 | 0.66 | MEN1 (0.30) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL9066108 | 0.64 | NQO2 (0.51) | NQO2RAB9APTGS1RELAAPP | |
| SCHEMBL7207966 | 0.63 | KMT2A (0.51) | KDM4E | |
| SCHEMBL140015 | 0.59 | RELA (0.54) | NQO2RAB9APTGS1RELAMAPT | |
| SCHEMBL7805362 | 0.58 | RELA (0.52) | NQO2RAB9APTGS1RELAMAPT | |
| SCHEMBL28140562 | 0.58 | RELA (0.52) | NQO2RAB9APTGS1RELAMAPT | |
| SCHEMBL9527298 | 0.58 | RELA (0.52) | NQO2RAB9APTGS1RELAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817690-A | ANTIDOPAMINE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |