Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 3/20 | 0.43 |
| ▸ | MC5R | P33032 | 3/20 | 0.43 |
| ▸ | MC3R | P41968 | 3/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862072 | 1.00 | AGER (0.47) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL3370759 | 0.88 | AGER (0.55) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL77425 | 0.84 | MC4R (0.54) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL738277 | 0.84 | MC4R (0.54) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL736913 | 0.82 | AGER (0.50) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL736914 | 0.82 | AGER (0.50) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL2400009 | 0.81 | OPRM1 (0.51) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL13275447 | 0.81 | OPRM1 (0.51) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL2400012 | 0.81 | OPRM1 (0.51) | AGERMTNR1ACHRM2CHRM3OPRM1 | |
| SCHEMBL481562 | 0.80 | YTHDC1 (0.49) | MEN1KMT2AMC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432760-A1 | BRIDGED SPIRO [2.4]HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-03-28 | — | — | EP | disclosed |