Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908771 | 0.85 | ACE (0.61) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL4573235 | 0.85 | ACE (0.61) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL3840630 | 0.85 | ACE (0.61) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL28561301 | 0.82 | ACE (0.48) | ACEPOLBTDP1L3MBTL1PREP | |
| SCHEMBL4480032 | 0.79 | NR1D1 (0.49) | NR1D1ACEPOLBTDP1L3MBTL1 | |
| SCHEMBL4627296 | 0.77 | ACE (0.60) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL5720519 | 0.77 | ACE (0.60) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL25377457 | 0.77 | PREP (0.69) | PREP | |
| SCHEMBL3891147 | 0.77 | TACR1 (0.47) | NR1D1ACEPOLBTDP1L3MBTL1 | |
| SCHEMBL25349861 | 0.77 | TACR1 (0.47) | NR1D1ACEPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10291979-A | — | — | None | — | — | JP | disclosed |
| JP-H10291979-A | PRODUCTION OF 1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID TERTIARY BUTYL AMIDE | ICHIKAWA GOSEI KAGAKU KK | 1998-11-04 | — | — | JP | disclosed |