SCHEMBL4627296

SCHEMBL4627296

O=C(O)[C@@H]1Cc2ccccc2CN1C(=O)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACE P12821 5/20 0.60
POLB P06746 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CHEK1 O14757 1/20 0.49
JAK2 O60674 1/20 0.49
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
AGTR2 P50052 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5720519 1.00 ACE (0.60) ACEPOLBTDP1L3MBTL1CHEK1
SCHEMBL13193021 0.89 ACE (0.56) ACEPOLBTDP1L3MBTL1CHEK1
SCHEMBL16879223 0.88 ALDH1A1 (0.58) ACEPOLBTDP1L3MBTL1CHEK1
SCHEMBL2080858 0.85 ACE (0.59) ACEPOLBTDP1L3MBTL1CHEK1
SCHEMBL7274646 0.85 ACE (0.62) ACEPOLBTDP1L3MBTL1
SCHEMBL29707284 0.85 ACE (0.59) ACEPOLBTDP1L3MBTL1CHEK1
SCHEMBL14067913 0.85 ACE (0.59) ACEPOLBTDP1L3MBTL1CHEK1
SCHEMBL66871 0.85 ACE (0.59) ACEPOLBTDP1L3MBTL1CHEK1
SCHEMBL7274651 0.85 ACE (0.62) ACEPOLBTDP1L3MBTL1
SCHEMBL66872 0.85 ACE (0.59) ACEPOLBTDP1L3MBTL1CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1543074-B1 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP CO LTD (KR) 2008-02-27 EP claimed
US-7046904-B2 UV-curable resin composition for cladding optical fiber SSCP CO., LTD. (KR) 2006-05-16 US claimed
US-20060067638-A1 Uv-curable resin composition for cladding optical fiber LUVANTIX CO., LTD. (KR) 2006-03-30 US claimed
EP-1543074-B1 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP CO LTD (KR) 2008-02-27 EP disclosed
US-7046904-B2 UV-curable resin composition for cladding optical fiber SSCP CO., LTD. (KR) 2006-05-16 US disclosed
US-20060067638-A1 Uv-curable resin composition for cladding optical fiber LUVANTIX CO., LTD. (KR) 2006-03-30 US disclosed
US-6730289-B2 HAIR STYLING MIXTURE COMPRISING AN ACYLATED CARBAMATE GROUP MODIFIED POLYURETHANE AND ACCEPTABLE CARRIER OR DILUENT; NO DEPOSITS ON HAIR, WATER SOLUBLE UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-05-04 US disclosed
US-20020176837-A1 Cosmetic composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-11-28 US disclosed
WO-2002058645-A1 POLYURETHANES, COSMETIC COMPOSITIONS CONTAINING THEM AND METHOD OF PREPARATION UNILEVER PLC (GB) 2002-08-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020176837-A1 Cosmetic composition POLR1C, ALKBH5, HAT1 ACE 4540/4885POLB 259/4885TDP1 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.