SCHEMBL8621134

SCHEMBL8621134

CCOC(=O)c1cc(-c2nn(C)c(SC)c2Cl)c(Cl)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.46
BAZ2A Q9UIF9 1/20 0.46
TEAD2 Q15562 1/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
HPGD P15428 5/20 0.38
ALDH1A1 P00352 5/20 0.38
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
KMT2A Q03164 2/20 0.36
LMNA P02545 2/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857284 0.79 BAZ2B (0.41) BAZ2BBAZ2ATEAD2CA1CA2
SCHEMBL9856794 0.71 BAZ2B (0.40) BAZ2BBAZ2ATEAD2CA1CA2
SCHEMBL8621599 0.71 L3MBTL1 (0.33) CA1CA2CA12CA9POLB
SCHEMBL9857055 0.70 BAZ2B (0.33) BAZ2BBAZ2ACA1CA2CA12
SCHEMBL8598685 0.68 MAPT (0.33) BAZ2BBAZ2AHPGDALDH1A1MAPT
SCHEMBL8547745 0.68 BAZ2B (0.41) BAZ2BBAZ2ATEAD2CA1CA2
SCHEMBL7689950 0.68 GUSB (0.41) BAZ2BBAZ2ATEAD2CYP4F2CYP4A11
SCHEMBL2360683 0.67 RAB9A (0.49) HPGDALDH1A1MAPTKMT2ALMNA
SCHEMBL9856872 0.66 MAPT (0.36) HPGDALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL1812364 0.66 ALDH1A1 (0.54) BAZ2BBAZ2ACA1CA2CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443059-B1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO LTD (JP) 1998-06-17 EP disclosed
EP-0361114-B1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO LTD (JP) 1998-06-03 EP disclosed
EP-0443059-A1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1991-08-28 EP disclosed
US-5032165-A 3-(substituted phenyl)pyrazole derivatives, salts thereof, and herbicides therefrom NIHON NOHYAKU COMPANY, LTD. (JP) 1991-07-16 US disclosed
EP-0361114-A1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1990-04-04 EP disclosed