SCHEMBL9856794

SCHEMBL9856794

CCOC(=O)c1cc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.40
BAZ2A Q9UIF9 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 2/20 0.37
TEAD2 Q15562 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
JMJD6 Q6NYC1 1/20 0.37
GUSB P08236 1/20 0.37
GAA P10253 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9738493 0.93 GAA (0.39) BAZ2BBAZ2ASMN1; SMN2HPGDTEAD2
SCHEMBL9857284 0.92 BAZ2B (0.41) BAZ2BBAZ2ASMN1; SMN2HPGDTEAD2
SCHEMBL9856747 0.91 PPOX (0.35) BAZ2BBAZ2ASMN1; SMN2HPGDTEAD2
SCHEMBL9856930 0.89 GAA (0.35) SMN1; SMN2HPGDLMNAMAPTGUSB
SCHEMBL6433878 0.87 SMN1; SMN2 (0.33) SMN1; SMN2HPGDLMNAMAPTGAA
SCHEMBL4067916 0.86 NTRK1 (0.35)
SCHEMBL7974134 0.86 NTRK1 (0.33)
SCHEMBL27469166 0.86 PPOX (0.32) SMN1; SMN2LMNANPC1RAB9AKDM4E
SCHEMBL9857115 0.85 LMNA (0.35) SMN1; SMN2HPGDLMNAMAPTGAA
SCHEMBL6295364 0.83 PPOX (0.46) SMN1; SMN2HPGDLMNAMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443059-A1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1991-08-28 EP claimed
US-5032165-A 3-(substituted phenyl)pyrazole derivatives, salts thereof, and herbicides therefrom NIHON NOHYAKU COMPANY, LTD. (JP) 1991-07-16 US claimed
EP-0361114-A1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1990-04-04 EP claimed