Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8622313 | 0.99 | ITGB3 (0.38) | DRD2ITGB3ITGA2BNR3C1ITGA2 | |
| SCHEMBL10844338 | 0.74 | FAAH (0.44) | ITGB3ITGA2BBRD4 | |
| SCHEMBL8541899 | 0.74 | SLC6A2 (0.42) | DRD2NR3C1DRD3 | |
| Hydrochloric Acid SCHEMBL8549104 | 0.73 | ITGB3 (0.36) | DRD2ITGB3ITGA2BITGA2SMYD3 | |
| Hydrochloric Acid SCHEMBL8621616 | 0.71 | ITGB3 (0.41) | ITGB3ITGA2BFLT3DGAT1 | |
| Hydrochloric Acid SCHEMBL8621613 | 0.71 | ITGB3 (0.41) | ITGB3ITGA2BFLT3DGAT1 | |
| SCHEMBL9235042 | 0.70 | POLB (0.51) | DRD2DRD3 | |
| SCHEMBL9237279 | 0.69 | DRD2 (0.43) | DRD2DRD3 | |
| SCHEMBL9238418 | 0.69 | POLB (0.53) | DRD2DRD3 | |
| SCHEMBL9236118 | 0.68 | ITGB3 (0.45) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |