Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.43 |
| ▸ | DRD3 | P35462 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236118 | 0.87 | ITGB3 (0.45) | TSHRPOLBTPSAB1TPSD1TPSG1 | |
| Bicarbonate SCHEMBL9237284 | 0.86 | POLB (0.53) | DRD2DRD3TSHRPOLBPKM | |
| Bicarbonate SCHEMBL9239335 | 0.85 | POLB (0.52) | DRD2DRD3TSHRPOLBPKM | |
| SCHEMBL9235042 | 0.84 | POLB (0.51) | DRD2DRD3POLBHTR1AHTR2A | |
| SCHEMBL9238418 | 0.82 | POLB (0.53) | DRD2DRD3POLBHTR1AHTR2A | |
| SCHEMBL9235050 | 0.77 | POLB (0.38) | TSHRPOLBTPSAB1TPSD1TPSG1 | |
| SCHEMBL22291286 | 0.77 | ITGB3 (0.46) | DRD2DRD3TPSAB1TPSD1TPSG1 | |
| SCHEMBL9239309 | 0.75 | POLB (0.38) | TSHRPOLBTPSAB1TPSD1TPSG1 | |
| Bicarbonate SCHEMBL9236121 | 0.73 | HTT (0.55) | TSHRPOLBPKMKDM4EALDH1A1 | |
| Bicarbonate SCHEMBL9238422 | 0.72 | DRD2 (0.57) | DRD2DRD3TSHRPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |