Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619451 | 0.87 | RXRA (0.53) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL8617222 | 0.80 | CDK4 (0.44) | FFAR4RXRARXRBRXRGMAOB | |
| SCHEMBL9777771 | 0.78 | RXRA (0.49) | RXRARXRBRXRGHIF1AMRGPRX4 | |
| SCHEMBL12301142 | 0.76 | ABCB1 (0.67) | HTR1AABCB1DRD2ADRA1DADRA1A | |
| SCHEMBL8618929 | 0.74 | MRGPRX4 (0.55) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL8618926 | 0.74 | MRGPRX4 (0.55) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL8622477 | 0.74 | L3MBTL1 (0.46) | HIF1AHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8624710 | 0.74 | MRGPRX4 (0.51) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL8624707 | 0.74 | MRGPRX4 (0.51) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL8618317 | 0.73 | PTPN1 (0.43) | HIF1AHTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |