SCHEMBL8622084

SCHEMBL8622084

C/C=C/C(=O)O[C@H]1CC[C@H]([C@H]2CC[C@H](C(=O)O[C@H]3CC[C@H](CCC)CC3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.33
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624341 0.96 NAAA (0.33) NAAA
SCHEMBL8617373 0.93 NAAA (0.40) NAAA
SCHEMBL8621538 0.91 PKM (0.38) NAAA
SCHEMBL8622442 0.90 HTT (0.39) NAAA
SCHEMBL8622958 0.90 HTT (0.39) NAAA
SCHEMBL9184402 0.90 CYP19A1 (0.36)
SCHEMBL8624148 0.88 NAAA (0.42) NAAA
SCHEMBL10844754 0.88 TLR4 (0.39) TLR4NAAA
SCHEMBL9561988 0.88 TLR4 (0.39) TLR4NAAA
SCHEMBL11040168 0.88 TLR4 (0.39) TLR4NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595144-B1 Cyclohexyl alkenoates as components of liquid crystalline mixtures MERCK PATENT GMBH (DE) 1998-05-20 EP disclosed
US-5380462-A Cyclohexyl alkenoate compounds HOFFMANN-LA ROCHE INC. (US) 1995-01-10 US disclosed
EP-0595144-A1 Cyclohexyl alkenoates as components of liquid crystalline mixtures F. HOFFMANN-LA ROCHE AG (CH) 1994-05-04 EP disclosed