Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29006124 | 0.91 | MAPT (0.52) | MAPTALDH1A1L3MBTL1CYP3A4MAOA | |
| SCHEMBL20679041 | 0.89 | NR4A1 (0.50) | MAPTALDH1A1L3MBTL1CYP3A4MAOA | |
| SCHEMBL29088062 | 0.86 | MAOA (0.63) | MAPTALDH1A1L3MBTL1CYP3A4MAOA | |
| SCHEMBL251644 | 0.84 | ALDH1A1 (0.43) | MAPTALDH1A1L3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL8896647 | 0.80 | ALDH1A1 (0.41) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL19411968 | 0.79 | ALDH1A1 (0.43) | MAPTALDH1A1L3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL4068582 | 0.78 | HPGD (0.52) | MAPTALDH1A1L3MBTL1HTTALOX12 | |
| SCHEMBL29006127 | 0.78 | MAOB (0.57) | MAPTALDH1A1CYP3A4MAOAHTT | |
| SCHEMBL15839989 | 0.78 | MEN1 (0.57) | MAPTALDH1A1CYP3A4MAOARAB9A | |
| SCHEMBL23045906 | 0.77 | TAAR1 (0.46) | MAPTALDH1A1CYP3A4MAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10045690-A | — | — | None | — | — | JP | disclosed |
| JP-H1045690-A | BIS-SUBSTITUTED PHENOXYPHENYLENEDIAMINE DERIVATIVE AND PRODUCTION THEREOF | NISSAN CHEM IND LTD | 1998-02-17 | — | — | JP | disclosed |