Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626716 | 0.99 | NPC1 (0.54) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8901444 | 0.89 | NPC1 (0.60) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9564275 | 0.79 | NPC1 (0.64) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8555090 | 0.79 | GPBAR1 (0.61) | ALOX5 | |
| SCHEMBL8557020 | 0.79 | GPBAR1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8556878 | 0.79 | PPARD (0.50) | NPC1RAB9AMAPTMEN1L3MBTL1 | |
| SCHEMBL8557214 | 0.78 | ADORA3 (0.47) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8554930 | 0.78 | GPBAR1 (0.62) | ALOX5 | |
| SCHEMBL8555940 | 0.76 | ADORA3 (0.41) | RAB9AMAPTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL8557149 | 0.76 | KMT2A (0.38) | NPC1RAB9AMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |