Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557214 | 0.89 | ADORA3 (0.47) | PPARDPPARAALOX5MAPTL3MBTL1 | |
| SCHEMBL8555940 | 0.84 | ADORA3 (0.41) | PPARDALOX5MAPTTDP1RAB9A | |
| SCHEMBL8557149 | 0.82 | KMT2A (0.38) | MAPTL3MBTL1RAB9AADORA3POLB | |
| SCHEMBL8626716 | 0.80 | NPC1 (0.54) | ALOX5MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL8622650 | 0.79 | NPC1 (0.53) | ALOX5MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL8559076 | 0.76 | KMT2A (0.40) | ALOX5MAPTTDP1RAB9APOLB | |
| SCHEMBL8559814 | 0.75 | PARP10 (0.45) | ADORA3MEN1NPC1 | |
| SCHEMBL8554714 | 0.74 | PARP10 (0.57) | MAPTPOLBKDM4EMEN1 | |
| SCHEMBL8557020 | 0.74 | GPBAR1 (0.46) | ALOX5MAPTRAB9ANPC1 | |
| SCHEMBL8554930 | 0.73 | GPBAR1 (0.62) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |