Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM4B | O94953 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556878 | 0.89 | PPARD (0.50) | ADORA3MAPTL3MBTL1ALOX5KDM4E | |
| SCHEMBL8559814 | 0.84 | PARP10 (0.45) | ADORA3NPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8554714 | 0.80 | PARP10 (0.57) | MAPTALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL8626716 | 0.79 | NPC1 (0.54) | MAPTL3MBTL1ALDH1A1PKMALOX5 | |
| SCHEMBL8622650 | 0.78 | NPC1 (0.53) | MAPTL3MBTL1ALDH1A1PKMALOX5 | |
| SCHEMBL8555940 | 0.75 | ADORA3 (0.41) | ADORA3MAPTALDH1A1ALOX5KDM4E | |
| SCHEMBL8557149 | 0.75 | KMT2A (0.38) | ADORA3MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8557020 | 0.73 | GPBAR1 (0.46) | MAPTALOX5NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8554930 | 0.72 | GPBAR1 (0.62) | ALOX5 | |
| SCHEMBL8557961 | 0.72 | MAPT (0.42) | ADORA3MAPTL3MBTL1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |