Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622676 | 0.80 | HTR2B (0.51) | HTR6EGFRPIK3CAMTORHTR2C | |
| SCHEMBL6714734 | 0.73 | HTR6 (0.54) | HTR6HTR2CHTR2A | |
| SCHEMBL6719408 | 0.70 | HDAC3 (0.52) | HTR6HTR2CMAPTHTR2A | |
| SCHEMBL8710351 | 0.67 | MAPT (0.62) | HTR2CHTR2BKDM4EMEN1TP53 | |
| SCHEMBL7258134 | 0.65 | HTR1D (0.67) | HTR6HTR2CHTR2A | |
| SCHEMBL21671857 | 0.65 | HTR6 (0.58) | HTR6EGFRHTR2CHTR2A | |
| SCHEMBL9400613 | 0.65 | HTR2B (0.65) | HTR2CHTR2BKDM4EMEN1TP53 | |
| SCHEMBL18960579 | 0.64 | HTR2C (0.56) | HTR6HTR2CCYP1A2CYP2D6HTR2A | |
| SCHEMBL8615090 | 0.64 | HTR6 (0.49) | HTR6PIK3CAMTORHTR2CHTR2B | |
| SCHEMBL9400583 | 0.64 | MEN1 (0.73) | HTR2CHTR2BKDM4EMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998047868-A1 | HETEROCYCLE-CONTAINING UREA DERIVATIVES AS 5HT1A, 5HT1B AND 5HT1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-29 | — | — | WO | disclosed |