Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8951774 | 0.80 | HTR6 (0.38) | HTR6HTR2AKDM4ELMNACYP1A2 | |
| SCHEMBL1133136 | 0.75 | GABRA1 (0.34) | HTR6GABRA1GABRB2TOP2A | |
| SCHEMBL5353138 | 0.73 | HTR2A (0.64) | HTR2AKDM4ELMNACYP3A4CYP2D6 | |
| SCHEMBL3799595 | 0.72 | HTR2A (0.48) | HTR2AKDM4ELMNACYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8623493 | 0.71 | HTR2A (0.34) | HTR2A | |
| SCHEMBL5669994 | 0.69 | HTR2A (0.45) | HTR2AKDM4ELMNACYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6557729 | 0.69 | HTR2A (0.58) | HTR2AKDM4ELMNACYP3A4CYP2D6 | |
| SCHEMBL9161284 | 0.68 | HTR2A (0.44) | HTR2AKDM4ELMNACYP3A4CYP2D6 | |
| SCHEMBL252162 | 0.68 | HTR2A (0.52) | HTR2ACA1CA2TDO2 | |
| SCHEMBL822007 | 0.68 | TOP2A (0.34) | HTR6KDM4ELMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854363-A | (Omega-alkenyl) (cyclopentacarbyl) metallocene compounds | PHILLIPS PETROLEUM COMPANY (US) | 1998-12-29 | — | — | US | disclosed |