Sugi Predict

Sugi Predict / Compounds / SCHEMBL822007

SCHEMBL822007

SCHEMBL822007

C=CCC1=CC([Si](C)(C)C)c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TOP2A P11388 1/20 0.34
▸ GABRA1 P14867 1/20 0.33
▸ GABRB2 P47870 1/20 0.33
▸ HTR6 P50406 3/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ CYP2D6 P10635 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ ALOX15 P16050 1/20 0.30
▸ ALOX12 P18054 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8466889 0.84 TOP2A (0.32) TOP2A
SCHEMBL7781755 0.82 HTR6 (0.40) HTR6
SCHEMBL6910596 0.82 HTR6 (0.36) HTR6
Hydrochloric Acid SCHEMBL8680298 0.82 TOP2A (0.30) TOP2A
SCHEMBL8951774 0.72 HTR6 (0.38) TOP2AGABRA1GABRB2HTR6KDM4E
SCHEMBL2463207 0.72 HRH3 (0.38) HTR6LMNAALOX15
SCHEMBL7542646 0.71 GPR3 (0.34) GAAALOX15
SCHEMBL7542082 0.69 GPR3 (0.33) ALOX15
SCHEMBL29979921 0.69 GPR3 (0.33) ALOX15
Ethylene SCHEMBL10454772 0.69 GPR3 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367853-B2 Method and system for forming a precursor compound for non-bridged unsymmetric polyolefin polymerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-02-05 — — US disclosed
US-20110275848-A1 METHOD AND SYSTEM FOR FORMING A PRECURSOR COMPOUND FOR NON-BRIDGED UNSYMMETRIC POLYOLEFIN POLYMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-11-10 — — US disclosed
US-8013177-B2 Method and system for forming a precursor compound for non-bridged unsymmetric polyolefin polymerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-09-06 — — US disclosed
US-20100292425-A1 METHOD AND SYSTEM FOR FORMING A PRECURSOR COMPOUND FOR NON-BRIDGED UNSYMMETRIC POLYOLEFIN POLYMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292425-A1 METHOD AND SYSTEM FOR FORMING A PRECURSOR COMPOUND FOR NON-BRIDGED UNSYMMETRIC POLYOLEFIN POLYMERIZATION CATALYST DHPS, PCBP1, GGPS1 TOP2A 2129/4885GABRA1 3687/4885GABRB2 4140/4885
US-20110275848-A1 METHOD AND SYSTEM FOR FORMING A PRECURSOR COMPOUND FOR NON-BRIDGED UNSYMMETRIC POLYOLEFIN POLYMERIZATION CATALYST DHPS, PCBP1, GGPS1 TOP2A 2129/4885GABRA1 3687/4885GABRB2 4140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.