SCHEMBL1133136

SCHEMBL1133136

C=CCC1=CC(CCC2C=C(CC=C)c3cccc4cccc2c34)c2cccc3cccc1c23

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
HTR6 P50406 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TOP2A P11388 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1396175 0.78 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL8622898 0.75 HTR6 (0.40) GABRA1GABRB2HTR6TOP2A
SCHEMBL4565339 0.70 KMT2A (0.47) GABRA1GABRB2ALDH1A1TSHRMAPK1
SCHEMBL8951774 0.70 HTR6 (0.38) GABRA1GABRB2HTR6TOP2A
SCHEMBL3764804 0.68 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL9323927 0.68 GABRA1 (0.40) GABRA1GABRB2ALDH1A1HSD17B10
SCHEMBL11819501 0.67 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL16447706 0.66 HSD17B10 (0.37) ALDH1A1TSHRHSD17B10
SCHEMBL10915787 0.66 KDM4E (0.31) ALDH1A1TSHRMAPK1ATMHSD17B10
SCHEMBL4785447 0.64 MAPT (0.40) GABRA1GABRB2ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658835-B1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL CO (US) 2016-08-17 EP disclosed
CN-103270006-B Its method of olefin oligomerization catalyzer and preparation and use Chevron Phillips Chemical Co.,L.P. (US) 2016-04-27 CN disclosed
EP-2044093-B1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL CO (US) 2014-12-03 EP disclosed
EP-2289901-B1 Olefin oligomerization catalysts and methods of using same CHEVRON PHILLIPS CHEMICAL CO (US) 2014-07-09 EP disclosed
EP-2658835-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2013-11-06 EP disclosed
US-8334420-B2 Selectivity for hexene and octene from ethylene; polymerization inhibitor containing chromium, titanium and vanadium CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-12-18 US disclosed
US-20120172645-A1 Olefin Oligomerization catalysts and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-07-05 US disclosed
WO-2012092415-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-07-05 WO disclosed
EP-2289901-A1 Olefin oligomerization catalysts and methods of using same Chevron Phillips Chemical Company LP (US) 2011-03-02 EP disclosed
EP-2287172-A1 Olefin oligomerization catalysts and methods of using same Chevron Phillips Chemical Company LP (US) 2011-02-23 EP disclosed
EP-2044093-A2 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME Chevron Phillips Chemical Company LP (US) 2009-04-08 EP disclosed
US-20080207857-A1 Olefin Oligomerization Catalysts and Methods of Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-08-28 US disclosed
US-7378537-B2 Olefin oligomerization catalysts and methods of using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-05-27 US disclosed
WO-2008014139-A2 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-31 WO disclosed
US-20080027188-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172645-A1 Olefin Oligomerization catalysts and Methods of Making and Using Same COG7, COG8, COG4 GABRA1 3705/4885GABRB2 4182/4885HTR6 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.