SCHEMBL8618393

SCHEMBL8618393

CN(C)c1ccc(-c2cc(-c3ccc(N4CCCCC4)cc3)cc(-c3ccc(N(C)C)cc3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.44
TERT O14746 2/20 0.43
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
GLA P06280 1/20 0.42
MAPT P10636 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ACP1 P24666 1/20 0.42
MAP4K1 Q92918 1/20 0.41
ALK Q9UM73 1/20 0.40
KCNH2 Q12809 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
SYK P43405 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CHKA P35790 1/20 0.39
CNR1 P21554 1/20 0.38
APP P05067 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621175 0.99 MAPT (0.43) DHODHTERTALDH1A1HPGDKDM4E
SCHEMBL8621124 0.87 AHR (0.51) ALDH1A1HPGDKDM4ECYP1A2GLA
SCHEMBL8615949 0.84 TERT (0.40) DHODHTERTALDH1A1HPGDKDM4E
SCHEMBL8618775 0.81 MAPT (0.54) TERTALDH1A1KDM4EMAPTHSD17B10
SCHEMBL27363365 0.81 ALDH1A1 (0.53) TERTALDH1A1HPGDKDM4ECYP1A2
SCHEMBL10979077 0.81 KDM4E (0.41) ALDH1A1HPGDKDM4ECYP1A2GLA
SCHEMBL8622919 0.81 ALDH1A1 (0.43) ALDH1A1HPGDKDM4ECYP1A2GLA
SCHEMBL8621114 0.80 KDM4E (0.56) DHODHALDH1A1HPGDKDM4EHSD17B10
Hydrochloric Acid SCHEMBL27659481 0.79 ALDH1A1 (0.55) TERTALDH1A1HPGDKDM4ECYP1A2
SCHEMBL2201868 0.79 ALDH1A1 (0.51) TERTALDH1A1HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed
US-4446321-A COLOR FORMERS, CARBON-FREE DUPLICATION STERLING DRUG INC. (US) 1984-05-01 US disclosed