SCHEMBL8615949

SCHEMBL8615949

Cc1cc(N2CCCC2)ccc1-c1cc(-c2ccc(N(C)C)cc2)nc(-c2ccc(N(C)C)cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 2/20 0.40
ALDH1A1 P00352 5/20 0.39
MAPT P10636 5/20 0.39
KDM4E B2RXH2 4/20 0.39
HPGD P15428 4/20 0.39
HSD17B10 Q99714 3/20 0.39
CYP1A2 P05177 1/20 0.39
GLA P06280 1/20 0.39
AHR P35869 1/20 0.38
KMT2A Q03164 2/20 0.37
APP P05067 1/20 0.37
ACP1 P24666 1/20 0.37
LMNA P02545 3/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
HCRTR1 O43613 1/20 0.37
GAA P10253 1/20 0.37
CASP1 P29466 1/20 0.36
RECQL P46063 1/20 0.36
CASP7 P55210 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621175 0.85 MAPT (0.43) TERTALDH1A1MAPTKDM4EHPGD
SCHEMBL8618393 0.84 DHODH (0.44) TERTALDH1A1MAPTKDM4EHPGD
SCHEMBL8621124 0.75 AHR (0.51) ALDH1A1MAPTKDM4EHPGDHSD17B10
SCHEMBL8622919 0.74 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EHPGDHSD17B10
SCHEMBL8615693 0.74 PSMB5 (0.49) ALDH1A1MAPTKDM4EHPGDKMT2A
SCHEMBL10975485 0.73 MEN1 (0.47) ALDH1A1MAPTKDM4EHPGDHSD17B10
SCHEMBL2201868 0.72 ALDH1A1 (0.51) TERTALDH1A1MAPTKDM4EHPGD
SCHEMBL9012579 0.70 SYK (0.41) TERTALDH1A1MAPTHSD17B10APP
SCHEMBL8618775 0.70 MAPT (0.54) TERTALDH1A1MAPTKDM4EHSD17B10
SCHEMBL27363365 0.70 ALDH1A1 (0.53) TERTALDH1A1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed
EP-0061128-B1 PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND SYSTEMS CONTAINING THEM STERLING DRUG INC. (US) 1985-09-04 EP disclosed
US-4446321-A COLOR FORMERS, CARBON-FREE DUPLICATION STERLING DRUG INC. (US) 1984-05-01 US disclosed
US-4363503-A FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS STERLING DRUG INC. (US) 1982-12-14 US disclosed
EP-0061128-A1 Pyridine compounds, process for their preparation and systems containing them STERLING DRUG INC. (US) 1982-09-29 EP disclosed