Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10930583 | 1.00 | MMP1 (0.31) | MMP1MMP2MMP3MMP7LMNA | |
| SCHEMBL7844221 | 0.92 | — | — | |
| SCHEMBL9670653 | 0.82 | LMNA (0.34) | LMNATSHR | |
| SCHEMBL9671675 | 0.82 | LMNA (0.34) | LMNATSHR | |
| SCHEMBL3642760 | 0.81 | — | — | |
| SCHEMBL8156594 | 0.81 | CPB2 (0.34) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL10811138 | 0.81 | — | — | |
| SCHEMBL6855585 | 0.78 | — | — | |
| SCHEMBL9306056 | 0.78 | — | — | |
| SCHEMBL8040279 | 0.78 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029923-A1 | PROCESS FOR THE PREPARATION OF MONO- AND BIS(PHOSPHOCHOLINE) DERIVATIVES WHICH HAVE ANTIFUNGAL ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1995-11-09 | — | — | WO | claimed |
| US-5811568-A | PHOSPHORYLATION | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-09-22 | — | — | US | disclosed |