Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 4/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671675 | 1.00 | LMNA (0.34) | LMNADNM1CA2SMPD1OPRM1 | |
| SCHEMBL27161209 | 1.00 | LMNA (0.34) | LMNADNM1CA2SMPD1OPRM1 | |
| SCHEMBL27160802 | 0.90 | FAAH (0.39) | LMNA | |
| SCHEMBL28427825 | 0.89 | ACE2 (0.36) | LMNACA2 | |
| SCHEMBL8839016 | 0.83 | GPR84 (0.39) | LMNAGPR84 | |
| SCHEMBL10811138 | 0.82 | — | — | |
| SCHEMBL8156594 | 0.82 | CPB2 (0.34) | LMNADNM1CA2TSHR | |
| SCHEMBL8057980 | 0.82 | CPB2 (0.34) | LMNADNM1CA2TSHR | |
| SCHEMBL3642760 | 0.82 | — | — | |
| SCHEMBL28903383 | 0.82 | CPB2 (0.34) | LMNADNM1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |