Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624562 | 0.85 | LMNA (0.51) | MAPK1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL27484059 | 0.78 | GAA (0.48) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL8591800 | 0.76 | CHRM2 (0.53) | MAPK1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL8623458 | 0.76 | DRD2 (0.61) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL8550662 | 0.75 | SCN1A (0.63) | MAPK1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL6543289 | 0.74 | OPRL1 (0.55) | MAPK1ALDH1A1LMNAPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL8549692 | 0.74 | SCN1A (0.61) | MAPK1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL12452433 | 0.72 | ALDH1A1 (0.76) | MAPK1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL15952851 | 0.72 | OPRL1 (0.63) | MAPK1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL3898508 | 0.71 | OPRL1 (0.79) | MAPK1ALDH1A1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871613-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996035666-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 1996-11-14 | — | — | WO | disclosed |