SCHEMBL862358

SCHEMBL862358

Cc1ccc2ccc3cc(C)c(C)nc3c2n1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.65
CCR5 P51681 2/20 0.65
RAB9A P51151 1/20 0.65
METAP2 P50579 1/20 0.44
CYP1A2 P05177 3/20 0.39
OPRK1 P41145 1/20 0.38
KMT2A Q03164 1/20 0.38
PARP1 P09874 1/20 0.38
GLO1 Q04760 2/20 0.36
CCR8 P51685 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
CASP6 P55212 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
CD38 P28907 1/20 0.33
AGTR1 P30556 1/20 0.33
PAX8 Q06710 1/20 0.33
SLC40A1 Q9NP59 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460375 0.89 CCR1 (0.43) CCR1CCR5RAB9ACYP1A2KMT2A
Neocuproine SCHEMBL124563 0.81 CCR1 (1.00) CCR1CCR5RAB9AMETAP2CYP1A2
Neocuproine SCHEMBL11672280 0.81 CCR1 (1.00) CCR1CCR5RAB9AMETAP2CYP1A2
Neocuproine SCHEMBL29367091 0.81 CCR1 (1.00) CCR1CCR5RAB9AMETAP2CYP1A2
Neocuproine SCHEMBL29639703 0.81 CCR1 (1.00) CCR1CCR5RAB9AMETAP2CYP1A2
SCHEMBL10700123 0.79 CCR1 (0.60) CCR1CCR5RAB9AMETAP2CYP1A2
SCHEMBL15593262 0.79 CCR1 (0.38) CCR1CCR5RAB9ACCR8
SCHEMBL3225066 0.78 CCR1 (0.58) CCR1CCR5RAB9AMETAP2CYP1A2
Neocuproine SCHEMBL17926728 0.78 CCR1 (0.94) CCR1CCR5RAB9AMETAP2CYP1A2
Neocuproine SCHEMBL870750 0.78 CCR1 (0.94) CCR1CCR5RAB9AMETAP2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20160372675-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-9472763-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-10-18 US disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 US disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 US disclosed
US-20120205596-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-8142908-B2 Polymer light-emitting material comprising a conjugated polymer and compound exhibiting light emission from the triplet excited state and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-27 US disclosed
US-20120008068-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-8012603-B2 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-06 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080118773-A1 Complex Composition, Polymer Complex Compound And Polymer Light-Emitting Device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-22 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070103059-A1 Composition and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 CCR1 70/4885CCR5 521/4885RAB9A 1795/4885
US-20160372675-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 CCR1 288/4885CCR5 2067/4885RAB9A 3057/4885
US-20120205596-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 CCR1 288/4885CCR5 2067/4885RAB9A 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.