Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651711 | 0.84 | NR1H4 (0.54) | NR1H4LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL6325877 | 0.81 | NQO2 (0.51) | LMNACYP1A2NPC1RAB9AKDM4E | |
| SCHEMBL6325874 | 0.81 | NQO2 (0.51) | LMNACYP1A2NPC1RAB9AKDM4E | |
| SCHEMBL7462863 | 0.79 | MTNR1A (0.50) | — | |
| SCHEMBL7462866 | 0.79 | MTNR1A (0.50) | — | |
| SCHEMBL8497644 | 0.76 | GAA (0.50) | LMNAKDM4EGAAALDH1A1PKM | |
| SCHEMBL6955487 | 0.76 | NR1H4 (0.70) | NR1H4LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8913229 | 0.75 | MEN1 (0.62) | NR1H4LMNANPC1RAB9AKDM4E | |
| SCHEMBL8913233 | 0.75 | MEN1 (0.62) | NR1H4LMNANPC1RAB9AKDM4E | |
| SCHEMBL10990566 | 0.75 | LMNA (0.59) | NR1H4LMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750576-A | BONE DISORDERS | ORION-YHTYMA OY (FI) | 1998-05-12 | — | — | US | disclosed |