Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448659 | 0.89 | CNR1 (0.52) | LMNAPTGER4ALDH1A1CNR1CNR2 | |
| SCHEMBL8522667 | 0.87 | PTGER4 (0.58) | LMNAPTGER4SMN1; SMN2POLBMCL1 | |
| SCHEMBL8445572 | 0.86 | LMNA (0.51) | LMNAPTGER4ALDH1A1PLA2G2APOLB | |
| SCHEMBL8448874 | 0.85 | MAPT (0.49) | LMNAPTGER4ALDH1A1CNR1CNR2 | |
| SCHEMBL8441605 | 0.84 | PTGS2 (0.50) | PTGER4CNR1CNR2PLA2G2ATSHR | |
| SCHEMBL6966885 | 0.84 | KDM4E (0.50) | LMNAPTGER4SMN1; SMN2CNR1CNR2 | |
| SCHEMBL8627206 | 0.83 | BUB1 (0.44) | PTGER4ALDH1A1CNR1CNR2PTGDR2 | |
| SCHEMBL8310022 | 0.82 | CCR2 (0.50) | LMNAPTGER4ALDH1A1CNR1CNR2 | |
| SCHEMBL8450448 | 0.82 | AKR1C3 (0.51) | PTGER4CNR1CNR2PLA2G2APTGDR2 | |
| SCHEMBL8521077 | 0.82 | CCR9 (0.47) | PTGER4SMN1; SMN2CNR1CNR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | claimed |
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | disclosed |