SCHEMBL862490

SCHEMBL862490

Cc1ccc2oc3cc(C)c(C)cc3c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
HTT P42858 1/20 0.43
KDM4E B2RXH2 6/20 0.42
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 3/20 0.42
TP53 P04637 3/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 3/20 0.42
NQO1 P15559 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
MAPK1 P28482 2/20 0.41
KCNH2 Q12809 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALPG P10696 1/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
CSNK2A2 P19784 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19155599 0.89 MAPT (0.47) MAPTHTTKDM4EALDH1A1CYP3A4
SCHEMBL1610145 0.89 MAPT (0.50) MAPTHTTKDM4EALDH1A1CYP3A4
SCHEMBL862364 0.87 MAOB (0.46) MAPTHTTKDM4EALDH1A1TP53
SCHEMBL10141873 0.84 MAOB (0.47) MAPTHTTKDM4EALDH1A1CYP3A4
SCHEMBL25012692 0.84 ALDH1A1 (0.47) MAPTHTTKDM4EALDH1A1CYP3A4
SCHEMBL21325563 0.84 MAPT (0.42) MAPTHTTKDM4EALDH1A1CYP3A4
SCHEMBL22271444 0.84 MAPT (0.47) MAPTHTTKDM4EALDH1A1CYP3A4
SCHEMBL9927891 0.83 AHR (0.46) MAPTHTTKDM4EALDH1A1CYP3A4
SCHEMBL22738448 0.83 MAOB (0.46) MAPTHTTKDM4EALDH1A1CYP3A4
SCHEMBL10133860 0.80 MAPT (0.50) MAPTHTTKDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11063219-B2 Organic photoelectric conversion element, and solar cell module and sensor provided with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-07-13 US disclosed
US-10290809-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-05-14 US disclosed
US-20190115540-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL MODULE AND SENSOR PROVIDED WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-18 US disclosed
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20160372675-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
US-20160372675-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-20080118773-A1 Complex Composition, Polymer Complex Compound And Polymer Light-Emitting Device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-22 US disclosed
US-20080118773-A1 Complex Composition, Polymer Complex Compound And Polymer Light-Emitting Device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-22 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070103059-A1 Composition and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-20070103059-A1 Composition and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290809-B2 Macromolecular compound EXOSC4, TRPC6, MRPS22 MAPT 3843/4885HTT 3527/4885KDM4E 2826/4885
US-20160372675-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 MAPT 3843/4885HTT 3527/4885KDM4E 2826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.