Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624642 | 0.85 | KMT2A (0.41) | KMT2AKCNA3CYP1A2CYP2D6MAPT | |
| SCHEMBL9369385 | 0.79 | PIN1 (0.47) | PIN1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL27540519 | 0.77 | PIN1 (0.49) | PIN1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6779283 | 0.77 | PIN1 (0.49) | PIN1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6561186 | 0.75 | PIN1 (0.47) | PIN1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6562845 | 0.75 | PIN1 (0.47) | PIN1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL28360178 | 0.74 | POLB (0.47) | PIN1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL15991494 | 0.73 | EDNRB (0.46) | PIN1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL28101975 | 0.73 | EDNRB (0.46) | PIN1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL16629075 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AKCNA3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844992-A1 | PROCESS FOR PRODUCING $g(b)-AMINO-$g(a)-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | Degussa Aktiengesellschaft (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997002236-A1 | PROCESS FOR PRODUCING β-AMINO-α-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-01-23 | — | — | WO | disclosed |