SCHEMBL862529

SCHEMBL862529

Cc1ccc2c(c1C)c1c(C)cccc1n2C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
ALKBH5 Q6P6C2 1/20 0.40
FTO Q9C0B1 1/20 0.40
ALDH1A1 P00352 2/20 0.39
PKM P14618 2/20 0.39
LMNA P02545 1/20 0.39
IDO1 P14902 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
MDM2 Q00987 1/20 0.39
MCL1 Q07820 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GPR3 P46089 1/20 0.37
TRPA1 O75762 1/20 0.35
ATM Q13315 1/20 0.35
HTT P42858 2/20 0.35
ADORA3 P0DMS8 1/20 0.34
ADORA2A P29274 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14188336 0.87 ALKBH5 (0.48) MAPTKDM4EALKBH5FTOALDH1A1
SCHEMBL16203623 0.78 KDM4E (0.59) MAPTKDM4EALKBH5FTOALDH1A1
SCHEMBL22181379 0.78 MAPT (0.63) MAPTKDM4EALKBH5FTOALDH1A1
SCHEMBL29418964 0.75 MAPT (0.44) MAPTKDM4EALKBH5FTOALDH1A1
Iodide SCHEMBL6250148 0.73 MAPT (0.43) MAPTKDM4EALKBH5FTOALDH1A1
SCHEMBL4421580 0.73 MAPT (0.63) MAPTKDM4EALKBH5FTOALDH1A1
SCHEMBL22025584 0.72 MAPT (0.37) MAPTKDM4EALDH1A1MAPK1PIK3CD
SCHEMBL20115834 0.72 TSHR (0.48) MAPTKDM4EALKBH5FTOALDH1A1
SCHEMBL20115837 0.72 BCHE (0.48) MAPTKDM4EALKBH5FTOALDH1A1
Hydrochloric Acid SCHEMBL16046643 0.71 ALKBH5 (0.39) MAPTKDM4EALKBH5FTOALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160372675-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
US-9472763-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-10-18 US disclosed
US-20160152639-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-02 US disclosed
US-9290510-B2 Polymeric compound and electronic element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-22 US disclosed
US-9209404-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-08 US disclosed
US-9006714-B2 Photovoltaic device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-04-14 US disclosed
US-8772763-B2 Photovoltaic cell SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-08 US disclosed
US-20140020760-A1 METHOD OF PRODUCING ORGANIC PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-23 US disclosed
US-20120217448-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-30 US disclosed
US-20120205641-A1 PHOTOVOLTAIC CELL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-20120205593-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-20120205644-A1 PHOTOVOLTAIC CELL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-20120205596-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-8142908-B2 Polymer light-emitting material comprising a conjugated polymer and compound exhibiting light emission from the triplet excited state and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-27 US disclosed
US-20120008068-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160372675-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 MAPT 3843/4885KDM4E 2826/4885ALKBH5 3440/4885
US-20120205593-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT ARPC2, AXIN2, EMC2 MAPT 3153/4885KDM4E 1757/4885ALKBH5 2828/4885
US-20120205596-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 MAPT 3843/4885KDM4E 2826/4885ALKBH5 3440/4885
US-20160152639-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT ARPC2, AXIN2, EMC2 MAPT 3180/4885KDM4E 1742/4885ALKBH5 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.