SCHEMBL862546

SCHEMBL862546

CN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 1/20 0.63
FEN1 P39748 1/20 0.63
ERCC4 Q92889 1/20 0.63
ALDH1A1 P00352 5/20 0.62
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
KDM4E B2RXH2 3/20 0.62
HPGD P15428 3/20 0.62
HSD17B10 Q99714 2/20 0.62
CYP1B1 Q16678 1/20 0.62
HEXA P06865 5/20 0.58
HEXB P07686 5/20 0.58
USP2 O75604 2/20 0.56
KEAP1 Q14145 2/20 0.56
NFE2L2 Q16236 2/20 0.56
OGA O60502 1/20 0.56
ATM Q13315 1/20 0.56
LMNA P02545 1/20 0.56
CES2 O00748 1/20 0.56
BCHE P06276 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19450565 0.86 ERCC1 (0.53) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL1101925 0.85 KMT2A (0.62) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL12672646 0.85 ALDH1A1 (0.51) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL13206583 0.82 MPO (0.73) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL8927321 0.82 BRD1 (0.59) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL30072176 0.82 CYP1B1 (0.70) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL13009257 0.81 KMT2A (0.56) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL15243610 0.81 ALDH1A1 (0.55) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL4857545 0.81 KMT2A (0.56) ERCC1FEN1ERCC4ALDH1A1MEN1
SCHEMBL14463508 0.80 KDM4E (0.59) ERCC1FEN1ERCC4ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109535767-B Preparation method of perylene pigment 江苏丽王科技股份有限公司 2023-08-04 CN claimed
CN-109535767-A The preparation method of one germline pigment 江苏丽王科技股份有限公司 2019-03-29 CN claimed
US-20090215815-A1 Neurotrophin antagonist compositions PAINCEPTOR PHARMA CORPORATION (CA) 2009-08-27 US claimed
EP-0930883-B1 NEUROTROPHIN ANTAGONISTS FOR THE TREATMENT OF EPILEPSY, ALZHEIMER'S DISEASE AND PAIN ALLELIX BIOPHARMA (CA) 2006-01-11 EP claimed
US-20050250807-A1 Neurotrophin antagonist compositions TEHIM ASHOK 2005-11-10 US claimed
EP-1010731-B1 Process for the preparation of highly chromatic perylene pigments SUN CHEMICAL CORP (US) 2004-11-03 EP claimed
US-20020169182-A1 Neurotrophin antagonist compositions ALLELIX BIOPHARMACEUTICALS INC. (CA) 2002-11-14 US claimed
CN-1093645-C Photoresist material and method for producing semiconductor constituted of corrosion resist picture thereof NEC CORP (JP) 2002-10-30 CN claimed
EP-1217043-A2 Process for the preparation of perylene pigments Bayer Corporation (US) 2002-06-26 EP claimed
US-6403797-B1 REACTING MIXTURE COMPRISING PERYLENE TETRACARBOXYLIC COMPOUND, AMPHOTERIC SURFACTANT, AND EXCESS AMMONIA OR PRIMARY AMINE TO FORM INTERMEDIATE, HEATING IN PRESENCE OF NON-PIGMENTARY CYCLIC ANHYDRIDE OR IMIDE, COLLECTING PIGMENT BAYER CORPORATION 2002-06-11 US claimed
EP-1010731-A2 Process for the preparation of highly chromatic perylene pigments Bayer Corporation (US) 2000-06-21 EP claimed
US-6015458-A Process for the preparation of highly chromatic perylene pigments BAYER CORPORATION (US) 2000-01-18 US claimed
CN-1227355-A Photoresist material and method for producing semiconductor constituted of corrosion resist picture thereof NEC CORP (JP) 1999-09-01 CN claimed
EP-0930883-A1 NEUROTROPHIN ANTAGONIST COMPOSITIONS Allelix Biopharmaceuticals Inc. (CA) 1999-07-28 EP claimed
WO-1998017278-A1 NEUROTROPHIN ANTAGONIST COMPOSITIONS ALLELIX BIOPHARMACEUTICALS INC. (CA) 1998-04-30 WO claimed
US-12043749-B2 Method for producing ink composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-23 US disclosed
US-12043749-B2 Method for producing ink composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-23 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
EP-0019749-A1 Process for optical bleaching and dyeing synthetic fibres HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215815-A1 Neurotrophin antagonist compositions NGF, NTRK2, BDNF ERCC1 4624/4885FEN1 4048/4885ERCC4 4849/4885
US-20050250807-A1 Neurotrophin antagonist compositions NGF, NTRK2, BDNF ERCC1 4702/4885FEN1 4282/4885ERCC4 4858/4885
US-20020169182-A1 Neurotrophin antagonist compositions NTRK2, NGF, BDNF ERCC1 4459/4885FEN1 4358/4885ERCC4 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.