Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625481 | 0.71 | TSHR (0.40) | FBP1KDM1ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4666032 | 0.68 | MCL1 (0.40) | FBP1KDM1AALDH1A1TSHRAKR1C3 | |
| SCHEMBL11073623 | 0.66 | FBP1 (0.48) | FBP1KDM1ANPC1RAB9AMAPT | |
| SCHEMBL17836924 | 0.66 | FBP1 (0.48) | FBP1KDM1ANPC1RAB9AMAPT | |
| SCHEMBL9245051 | 0.66 | FBP1 (0.48) | FBP1KDM1ANPC1RAB9AMAPT | |
| SCHEMBL9508726 | 0.65 | ALDH1A1 (0.39) | FBP1KDM1AALDH1A1TSHRAKR1C3 | |
| SCHEMBL1377680 | 0.65 | ALDH1A1 (0.48) | FBP1ALDH1A1TSHRAKR1C3AKR1C1 | |
| SCHEMBL40189 | 0.65 | FBP1 (0.52) | FBP1KDM1ANPC1RAB9AMAPT | |
| SCHEMBL6438925 | 0.65 | FBP1 (0.52) | FBP1KDM1ANPC1RAB9AMAPT | |
| SCHEMBL7184139 | 0.65 | FBP1 (0.52) | FBP1KDM1ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5233052-A | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0487870-A2 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |