Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626408 | 0.81 | POLB (0.47) | ERCC5FEN1NPC1RAB9AKMT2A | |
| SCHEMBL8631653 | 0.81 | CTSD (0.53) | NPC1RAB9AHPGDLMNASMN1; SMN2 | |
| SCHEMBL3198121 | 0.76 | TSHR (0.52) | ERCC5FEN1NPC1RAB9AKMT2A | |
| SCHEMBL10429068 | 0.73 | CXCR5 (0.44) | KMT2AMEN1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL27743174 | 0.73 | VCP (0.59) | ERCC5FEN1NPC1RAB9AKMT2A | |
| SCHEMBL15841077 | 0.73 | FFAR1 (0.45) | ERCC5FEN1NPC1RAB9AHPGD | |
| SCHEMBL29702037 | 0.72 | TSHR (0.63) | ERCC5FEN1NPC1RAB9AKMT2A | |
| SCHEMBL101601 | 0.72 | TSHR (0.63) | ERCC5FEN1NPC1RAB9AKMT2A | |
| SCHEMBL11643111 | 0.71 | HPGD (0.46) | ERCC5FEN1KMT2AHPGDPOLB | |
| Hydrochloric Acid SCHEMBL17476094 | 0.71 | TSHR (0.61) | NPC1RAB9AKMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646570-B1 | PROCESS FOR PRODUCING LIGNAN COMPOUND | SHIONOGI & CO (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5488134-A | Preparation of compounds of lignan series | SHIONOGI & CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |
| EP-0646570-A1 | PROCESS FOR PRODUCING LIGNAN COMPOUND | SHIONOGI & CO., LTD. (JP) | 1995-04-05 | — | — | EP | disclosed |