Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.56 |
| ▸ | TUBB | P07437 | 2/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075690 | 0.95 | TUBB4A (0.60) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8628025 | 0.94 | ESR1 (0.76) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8630381 | 0.92 | ESR1 (0.80) | ESR1CNR1ESR2LMNA | |
| SCHEMBL7075680 | 0.90 | CNR1 (0.69) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7075343 | 0.88 | CNR1 (0.69) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22190469 | 0.88 | CNR1 (0.69) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7148725 | 0.86 | CNR1 (0.70) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11547223 | 0.84 | ESR1 (0.63) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26158897 | 0.84 | ESR1 (0.79) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26625282 | 0.83 | TUBB4A (0.60) | ESR1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780648-A | Benzothiophene compounds, and uses formulations thereof | ELI LILLY AND COMPANY (US) | 1998-07-14 | — | — | US | disclosed |