Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984392 | 0.83 | TDP1 (0.51) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL7654986 | 0.80 | P2RX7 (0.48) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL11497205 | 0.78 | CASP1 (0.52) | — | |
| SCHEMBL234454 | 0.75 | LMNA (0.62) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL3068668 | 0.74 | LMNA (0.57) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL8815917 | 0.73 | SLC6A2 (0.61) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL550351 | 0.72 | NPC1 (0.60) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL8775653 | 0.72 | LMNA (0.59) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL4704316 | 0.70 | POLB (0.45) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL2295789 | 0.70 | CA12 (0.66) | NPC1RAB9APOLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815074-A1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1998-01-07 | — | — | EP | disclosed |