Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | CES1 | P23141 | 2/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974595 | 0.91 | CES2 (0.58) | CES2CES1CA1CA2MAPT | |
| SCHEMBL7953 | 0.82 | CES2 (0.69) | CES2CES1CA4CA1CA2 | |
| SCHEMBL9723456 | 0.82 | CES2 (0.69) | CES2CES1CA4CA1CA2 | |
| SCHEMBL68050 | 0.82 | CES2 (0.69) | CES2CES1CA4CA1CA2 | |
| SCHEMBL30741457 | 0.82 | CES2 (0.69) | CES2CES1CA4CA1CA2 | |
| SCHEMBL10518077 | 0.82 | CES2 (0.69) | CES2CES1CA4CA1CA2 | |
| SCHEMBL9102 | 0.82 | CES2 (0.69) | CES2CES1CA4CA1CA2 | |
| SCHEMBL68051 | 0.82 | CES2 (0.69) | CES2CES1CA4CA1CA2 | |
| SCHEMBL5788885 | 0.80 | CES2 (0.67) | CES2CES1CA4CA1CA2 | |
| SCHEMBL1866929 | 0.79 | CA1 (0.60) | CES2CES1CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE28698-E | Electrophotographic material containing sensitizers | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1976-01-27 | — | — | US | claimed |
| JP-62092961-A | — | — | None | — | — | JP | disclosed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| JP-S6292961-A | LAMINATED ELECTROPHOTOGRAPHIC SENSITIVE BODY | MATSUSHITA ELECTRIC IND CO LTD | 1987-04-28 | — | — | JP | disclosed |
| US-RE28698-E | Electrophotographic material containing sensitizers | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1976-01-27 | — | — | US | disclosed |