Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624802 | 0.93 | KDM2B (0.39) | CHRNA7KMT2AKDM2BAPAF1CNR2 | |
| SCHEMBL8624540 | 0.91 | PGAM1 (0.40) | CHRNA7KMT2AKDM2BAPAF1CNR2 | |
| SCHEMBL8629280 | 0.90 | MITF (0.41) | CHRNA7KDM2BAPAF1LMNAMITF | |
| SCHEMBL8625789 | 0.90 | BRD4 (0.43) | CNR2CNR1DRD3DRD2 | |
| SCHEMBL8626990 | 0.90 | KDM2B (0.37) | CHRNA7KMT2AKDM2BAPAF1CNR2 | |
| SCHEMBL8624900 | 0.83 | APAF1 (0.38) | CHRNA7KMT2AAPAF1MITFDRD3 | |
| SCHEMBL8627347 | 0.83 | MITF (0.39) | CHRNA7APAF1MITFDRD3HRH3 | |
| SCHEMBL8625881 | 0.83 | BRD4 (0.45) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL8625633 | 0.83 | BRD4 (0.38) | CHRNA7APAF1MITFDRD3HRH3 | |
| SCHEMBL8630282 | 0.82 | PGAM1 (0.39) | CHRNA7APAF1MITFDRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |