Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627347 | 0.93 | MITF (0.39) | MITFCHRNA7APAF1CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL8625633 | 0.92 | BRD4 (0.38) | MITFCHRNA7APAF1CCNA2CDK2 | |
| SCHEMBL8630282 | 0.91 | PGAM1 (0.39) | MITFCHRNA7APAF1CCNA2CDK2 | |
| SCHEMBL8624822 | 0.90 | BRD4 (0.44) | GAARAD52DRD2HTR6BRD4 | |
| SCHEMBL8626684 | 0.90 | CHRNA7 (0.41) | MITFCHRNA7APAF1DRD3HRH3 | |
| SCHEMBL8628439 | 0.90 | CCNA2 (0.37) | MITFCHRNA7APAF1CCNA2CDK2 | |
| SCHEMBL8627298 | 0.90 | MITF (0.37) | MITFCHRNA7APAF1CCNA2CDK2 | |
| SCHEMBL7584069 | 0.85 | MITF (0.47) | MITFAPAF1GAAHTR6BRD4 | |
| SCHEMBL8624802 | 0.83 | KDM2B (0.39) | MITFCHRNA7APAF1DRD3HRH3 | |
| SCHEMBL8624605 | 0.83 | BRD4 (0.47) | GAARAD52BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |