Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.47 |
| ▸ | CTRC | Q99895 | 4/20 | 0.41 |
| ▸ | CMA1 | P23946 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400416 | 0.79 | ELANE (0.75) | ELANECTRC | |
| SCHEMBL8631836 | 0.68 | CTRC (0.34) | ELANECTRCCMA1 | |
| SCHEMBL8994538 | 0.68 | ELANE (0.73) | ELANECTRCCMA1 | |
| SCHEMBL7274343 | 0.64 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL7301006 | 0.64 | ELANE (0.38) | ELANECTRC | |
| SCHEMBL8628000 | 0.63 | HPGD (0.49) | — | |
| SCHEMBL2317449 | 0.62 | ELANE (0.56) | ELANECTRC | |
| SCHEMBL2317459 | 0.62 | ELANE (0.56) | ELANECTRC | |
| SCHEMBL7439651 | 0.62 | ELANE (0.77) | ELANECTRC | |
| SCHEMBL7440440 | 0.58 | ELANE (0.55) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636142-B1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | disclosed |