Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627255 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1ROCK2LMNA | |
| SCHEMBL1552751 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1ROCK2LMNA | |
| Hydrochloric Acid SCHEMBL8568583 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1ROCK2RXRA | |
| SCHEMBL8569965 | 0.75 | RAB9A (0.48) | SMN1; SMN2RAB9ANPC1ROCK2LMNA | |
| SCHEMBL8629601 | 0.74 | PDE4A (0.44) | ADORA2A | |
| SCHEMBL8627267 | 0.74 | RAB9A (0.41) | SMN1; SMN2RAB9ANPC1ROCK2LMNA | |
| SCHEMBL8568575 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1ROCK2LMNA | |
| SCHEMBL8628572 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1ROCK2KMT2A | |
| SCHEMBL1554630 | 0.69 | GAA (0.46) | SMN1; SMN2RAB9ANPC1ROCK2LMNA | |
| SCHEMBL8629585 | 0.69 | GAA (0.38) | SMN1; SMN2RAB9ANPC1ROCK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |